Tel: 585 63 4755, E-mail: lucie.hochvaldova@upol.cz, Room: 3.036 
Research interests
Synthesis and characterization of nanoparticles: Investigating the methods for synthesizing metal nanoparticles and their subsequent characterization to understand their physical and chemical properties.
Interaction of nanomaterials with biological systems: Exploring how nanomaterials interact with biological entities such as bacteria and cells, including the mechanisms of interaction and potential impacts on cellular processes.
Antibacterial activity and toxicity testing: Evaluating the ability of metal nanoparticles to exhibit antibacterial properties and conducting toxicity tests to assess their safety for biological systems.
Overall, bio-medical applications of nanoparticles with a central emphasis on combatting antibiotic resistance through the development of innovative antibacterial strategies.
Education
2018 – 2023 Palacky University in Olomouc, Faculty of Science; Doctoral study programme P1417 Chemistry, major Physical Chemistry, Dissertation: Interaction of nanostructured materials with living cells
2016 – 2018 Palacky University in Olomouc, Faculty of Science; Master’s degree programme N1407 Chemistry, major Material Chemistry; Master thesis: Study of controlled synthesis of silver nanoparticles
2013 – 2016 Palacky University in Olomouc, Faculty of Science; Bachelor study programme B1407 Chemistry, major Nanomaterials Chemistry; Bachelor thesis: Influence of redox potential of reducing agent on the synthesis of silver nanoparticles
Employment
2023 – now: Assistant professor, Department of Physical Chemistry, Faculty of Sciences, Palacky University Olomouc
2019 – 2023: Junior researcher, Department of Physical Chemistry, Faculty of Sciences, Palacky University Olomouc
International experience
02/2023, Paris Lodron University of Salzburg, Department of Microbiology. Infectious experiments. Studied the effect of silver nanoparticles on the H. pylori virulence.
09/2022, Paris Lodron University of Salzburg, Department of Microbiology. Follow-up to the previous internship, testing antibacterial activity with a focus on the bacterial strain H. pylori.
09-12/2021, Paris Lodron University of Salzburg, Department of Microbiology. Foreign internship. Focused on the evaluation of the antibacterial activity of silver nanoparticles against gastrointestinal pathogens and studying of their toxicity.
Cooperation
Renata Večeřová, Milan Kolář – Department of Microbiology, Faculty of Medicine, Palacky University, Olomouc, CZ – antibacterial activity testing
Sija Wessler, Gernot Posselt – Microbial Infection and Cancer, University of Salzburg, Austria – H. pylori research
Grants, projects, awards, memberships
Collaboration on following projects:
- 2019-2021 GAČR 19-22720S Novel Nano-structured Materials for Elimination of Highly- and Multi-resistant Bacteria and for Overcoming Antibiotic Resistance
- 2020-2023, MZ0/NU NU20-05-00165 Possibilities of Silver Nanoparticles Potentiated Antibiotherapy in the Treatment of Serious Bacterial Infections – in vitro and in vivo study
- 2022, UPOL, DSGC-2021-0120 Light-assisted in vitro therapy using plasmonic nanomaterials (IGRÁČEK)
