Mgr. Ing. Václav Bazgier, Ph.D.

@article{Dak2022,

title = {Novel heterocyclic hydroxamates as inhibitors of the mycobacterial zinc metalloprotease Zmp1 to probe its mechanism of function.},

author = {Milan Dak and Veronika Šlachtová and Marek Šebela and Václav Bazgier and Karel Berka and Natalia Smiejkowska and Lauren Oorts and Davie Cappoen and Lucie Brulíková},

url = {https://www.sciencedirect.com/science/article/pii/S0223523422007334#!},

doi = {10.1016/j.ejmech.2022.114831},

year  = {2022},

date = {2022-10-05},

journal = {Eur. J. Med. Chem.},

volume = {ASAP},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sehnal2021,

title = {Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures.},

author = {David Sehnal and Sebastian Bittrich and Mandar Deshpande and Radka Svobodová and Karel Berka and Václav Bazgier and Sameer Velankar and Stephen K Burley and Jaroslav Koča and Alexander S Rose},

doi = {10.1093/nar/gkab314},

year  = {2021},

date = {2021-05-06},

journal = {Nucleic Acids Res.},

volume = {49},

number = {W1},

pages = {W431-W437},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kiss2021,

title = {Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero)arylidene, pyrazolo[1,5-a]pyrimidine and triazolo[1,5-a]pyrimidine moieties and their targeting of the androgen receptor in prostate cancer.},

author = {Márton A. Kiss and Miroslav Peřina and Václav Bazgier and Nóra V May and Ádám Baji and Radek Jorda and Éva Frank},

doi = {10.1016/j.jsbmb.2021.105904},

year  = {2021},

date = {2021-04-29},

journal = {J. Steroid Biochem. Mol. Biol.},

volume = {211},

pages = {105904},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Špičáková2021,

title = {in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.},

author = {Alena Špičáková and Petr Kraus and Tomáš Gucký and Vladimír Kryštof and Miroslav Strnad and Václav Bazgier and Michal Otyepka and Vendula Kubíčková and Martin Poruba and Zuzana Rácová and Iveta Zapletalová and Pavel Anzenbacher},

doi = {10.33549/physiolres.934611},

year  = {2021},

date = {2021-03-01},

journal = {Physiol. Res.},

volume = {69},

number = {4},

pages = {S627-S636},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Diachkov2021,

title = {Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side Chain.},

author = {Mikhail V. Diachkov and Karoll Ferrer and Jana Oklešťková and Lucie Rarová and Václav Bazgier and Miroslav Kvasnica},

doi = {10.3390/ijms22010155},

year  = {2021},

date = {2021-01-01},

journal = {Int. J. Mol. Sci.},

volume = {22},

number = {1},

pages = {155},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Šlachtová2019,

title = {Novel thiazolidinedione-hydroxamates as inhibitors of Mycobacterium tuberculosis virulence factor Zmp1.},

author = {Veronika Šlachtová and Marek Šebela and Eveline Torfs and Lauren oorts and Davie Cappoen and Karel Berka and Václav Bazgier and Lucie Brulíková},

url = {https://www.sciencedirect.com/science/article/pii/S022352341930964X?fbclid=IwAR27lCE7YvC6P1V7ZzwQpxTEFeSV3evZ7YZJmx_Zhp_0szQGoU-gSyJ4foc#!},

doi = {10.1016/j.ejmech.2019.111812},

year  = {2020},

date = {2020-01-01},

journal = {Eur. J. Med. Chem.},

volume = {185},

pages = {111812},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Špičáková2019,

title = {Beta-caryophyllene oxide and trans-nerolidol affect enzyme activity of CYP3A4-in vitro and in silico studies.},

author = {Alena Špičáková and Václav Bazgier and L Skálová and Michal Otyepka and Pavel Anzenbacher},

doi = {10.33549/physiolres.934323},

year  = {2019},

date = {2019-12-04},

journal = {Physiol. Res.},

volume = {68},

pages = {S51-S58},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Juračka2019,

title = {MolMeDB: Molecules on Membranes Database.},

author = {Jakub Juračka and Martin Šrejber and Michaela Melíková and Václav Bazgier and Karel Berka},

doi = {10.1093/database/baz078},

year  = {2019},

date = {2019-06-27},

journal = {Database},

volume = {2019},

pages = {baz078},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jorda2019,

title = {Synthesis of novel galeterone derivatives and evaluation of their in vitro activity against prostate cancer cell lines.},

author = {Radek Jorda and Eva Řezníčková and Urszula Kiełczewska and Jadwiga Maj and Jacek Morzycki and Leszek Siergiejczyk and Václav Bazgier and Karel Berka and Lucie Rárová and Agnieszka Wojtkielewicz},

url = {https://www.sciencedirect.com/science/article/pii/S0223523419305665#!},

doi = {10.1016/j.ejmech.2019.06.040},

year  = {2019},

date = {2019-06-18},

journal = {Eur. J. Med. Chem.},

volume = {179},

pages = {483-492},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pravda2018,

title = {MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update).},

author = {Lukáš Pravda and David Sehnal and Dominik Toušek and Veronika Navrátilová and Václav Bazgier and Karel Berka and Radka Svobodová Vařeková and Jaroslav Koča and Michal Otyepka},

url = {https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky309/4990029},

doi = {10.1093/nar/gky309},

year  = {2018},

date = {2018-04-30},

journal = {Nucleic Acids Res},

volume = {46},

number = {W1},

pages = {W368–W373},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gucký2018,

title = {Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl-N6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 mutations.},

author = {Tomáš Gucký and Eva Řezníčková and Radosová Tereza Muchová and Radek Jorda and Zuzana Klejová and Veronika Malíková and Karel Berka and Václav Bazgier and Haresh Ajani and Martin Lepšík and Vladimír Divoký and Vladimír Kryštof},

url = {https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01529},

doi = {10.1021/acs.jmedchem.7b01529},

year  = {2018},

date = {2018-04-19},

journal = {J. Med. Chem.},

volume = {61},

number = {9},

pages = {3855–3869},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Šrejber2018,

title = {Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners.},

author = {Martin Šrejber and Veronika Navrátilová and Markéta Paloncýová and Václav Bazgier and Karel Berka and Pavel Anzenbacher and Michal Otyepka},

url = {https://www.sciencedirect.com/science/article/pii/S0162013417308413},

doi = {10.1016/j.jinorgbio.2018.03.002},

year  = {2018},

date = {2018-03-05},

journal = {J Inorg Biochem},

volume = {183},

pages = {117-136},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kořínková2017,

title = {Synthesis of novel aryl brassinosteroids through alkene cross-metathesis and preliminary biological study.},

author = {Petra Kořínková and Václav Bazgier and Jana Oklešťková and Lucie Rárová and Miroslav Strnad and Miroslav Kvasnica},

doi = {10.1016/j.steroids.2017.08.010},

year  = {2017},

date = {2017-08-21},

journal = {Steroids},

volume = {127},

pages = {46-55},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Huličiak2017,

title = {RH421 binds into the ATP-binding site on the Na+/K+-ATPase.},

author = {Miroslav Huličiak and Václav Bazgier and Karel Berka and Martin Kubala},

url = {http://www.sciencedirect.com/science/article/pii/S0005273617302419},

doi = {10.1016/j.bbamem.2017.07.016},

year  = {2017},

date = {2017-08-01},

journal = {Biochim. Biophys. Acta, Biomembranes},

volume = {1859},

number = {10},

pages = {2113–2122},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fernández2016b,

title = {Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.},

author = {Alejandro Carazo Fernández and Lucie Hyrsova and Jan Dušek and Hana Chodounská and Alžběta Horvátová and Karel Berka and Václav Bazgier and Hongying Gan-Schreier and Waleé Chamulitrat and Eva Kudová and Petr Pávek},

url = {http://www.sciencedirect.com/science/article/pii/S0378427416333021},

doi = {10.1016/j.toxlet.2016.11.013},

year  = {2017},

date = {2017-01-04},

journal = {Toxicol. Lett.},

volume = {265},

pages = {86–96},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bazgier2016,

title = {Exponential repulsion improves structural predictability of molecular docking.},

author = {Václav Bazgier and Karel Berka and Michal Otyepka and Pavel Banáš},

url = {http://onlinelibrary.wiley.com/doi/10.1002/jcc.24473/full},

doi = {10.1002/jcc.24473},

year  = {2016},

date = {2016-09-13},

journal = {J. Comput. Chem.},

volume = {37},

number = {28},

pages = {2485–2494},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kvasnica2016,

title = {Design, synthesis and biological activities of new brassinosteroid analogues with phenyl group in the side chain.},

author = {Miroslav Kvasnica and Jana Oklešťková and Václav Bazgier and Lucie Rárová and Petra Kořínková and Jaromír Mikulík and Miloš Buděšínský and Tibor Béres and Karel Berka and Qing Lu and Eugenia Russinova and Miroslav Strnad},

url = {http://pubs.rsc.org/en/content/articlelanding/2016/ob/c6ob01479h#!divAbstract},

doi = {10.1039/C6OB01479H},

year  = {2016},

date = {2016-08-17},

journal = {Org. Biomol. Chem.},

volume = {14},

number = {37},

pages = {8691-8701},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lamie2016,

title = {Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.},

author = {Phoebe F. Lamie and Waleed Ali Mohamed Ali and Václav Bazgier and Lucie Rárová},

url = {http://www.sciencedirect.com/science/article/pii/S0223523416306560},

doi = {10.1016/j.ejmech.2016.08.013},

year  = {2016},

date = {2016-08-10},

journal = {Eur. J. Med. Chem.},

volume = {123},

pages = {803–813},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nisler2016,

title = {Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase.},

author = {Jaroslav Nisler and David Kopečný and Radka Končitíková and Marek Zatloukal and Václav Bazgier and Karel Berka and David Zalabák and Pierre Briozzo and Miroslav Strnad and Lukáš Spíchal},

url = {http://link.springer.com/article/10.1007/s11103-016-0509-0},

doi = {10.1007/s11103-016-0509-0},

year  = {2016},

date = {2016-07-15},

journal = {Plant. Mol. Biol.},

volume = {92},

number = {1},

pages = {235–248},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Baltus2015,

title = {Synthesis, Biological Evaluation and Molecular Modeling of a Novel Series of 7-Azaindole Based Tri-Heterocyclic Compounds as Potent CDK2/Cyclin E Inhibitors.},

author = {Christine B. Baltus and Radek Jorda and Christophe Marot and Karel Berka and Václav Bazgier and Vladimír Kryštof and Gildas Prié and Marie-Claude Viaud-Massuard},

url = {http://www.sciencedirect.com/science/article/pii/S0223523415304116},

doi = {10.1016/j.ejmech.2015.12.023},

year  = {2016},

date = {2016-01-01},

journal = {Eur. J. Med. Chem.},

volume = {108},

number = {27},

pages = {701–719},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reznickova2015a,

title = {Characterization of a Pyrazolo[4,3- d ]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.},

author = {Eva Řezníčková and Sabine Weitensteiner and Libor Havlíček and Radek Jorda and Tomáš Gucký and Karel Berka and Václav Bazgier and Stefan Zahler and Vladimír Kryštof and Miroslav Strnad},

url = {http://doi.wiley.com/10.1111/cbdd.12618},

doi = {10.1111/cbdd.12618},

issn = {17470277},

year  = {2015},

date = {2015-09-01},

journal = {Chem. Biol. Drug. Des.},

volume = {86},

number = {6},

pages = {1528–1540},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reznickova2015,

title = {2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro.},

author = {Eva Řezníčková and Alexandr Popa and Tomáš Gucký and Marek Zatloukal and Libor Havlíček and Václav Bazgier and Karel Berka and Radek Jorda and Igor Popa and Abdelmajeed Nasereddin and Charles L. Jaffe and Vladimír Kryštof and Miroslav Strnad},

url = {http://linkinghub.elsevier.com/retrieve/pii/S0960894X15003509},

doi = {10.1016/j.bmcl.2015.04.030},

issn = {0960894X},

year  = {2015},

date = {2015-06-01},

journal = {Bioorg. Med. Chem. Lett.},

volume = {25},

number = {11},

pages = {2298-2301},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mojzych2014,

title = {Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazines.},

author = {Mariusz Mojzych and Veronika Šubertová and Anna Bielawska and Krzysztof Bielawski and Václav Bazgier and Karel Berka and Tomáš Gucký and Emilia Fornal and Vladimír Kryštof},

url = {http://linkinghub.elsevier.com/retrieve/pii/S0223523414002670},

doi = {10.1016/j.ejmech.2014.03.054},

issn = {02235234},

year  = {2014},

date = {2014-05-01},

journal = {Eur. J. Med. Chem.},

volume = {78},

pages = {217-224},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kvasnica2014,

title = {Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.},

author = {Miroslav Kvasnica and Jana Oklešťková and Václav Bazgier and Lucie Rárová and Karel Berka and Miroslav Strnad},

url = {http://linkinghub.elsevier.com/retrieve/pii/S0039128X14000786},

doi = {10.1016/j.steroids.2014.04.007},

issn = {0039128X},

year  = {2014},

date = {2014-01-01},

journal = {Steroids},

volume = {85},

pages = {58-64},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pozharitskaya2013,

title = {Antiallergic Effects of Pigments Isolated from Green Sea Urchin (Strongylocentrotus droebachiensis) Shells.},

author = {Olga Pozharitskaya and Alexander Shikov and Marina Makarova and Svetlana Ivanova and Vera Kosman and Valery Makarov and Václav Bazgier and Karel Berka and Michal Otyepka and Jitka Ulrichová},

url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1351098},

doi = {10.1055/s-0033-1351098},

issn = {0032-0943},

year  = {2013},

date = {2013-11-01},

journal = {Planta Med.},

volume = {79},

number = {18},

pages = {1698-1704},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gucky2013,

title = {A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors.},

author = {Tomáš Gucký and Radek Jorda and Marek Zatloukal and Václav Bazgier and Karel Berka and Eva Řezníčková and Tibor Béres and Miroslav Strnad and Vladimír Kryštof},

url = {http://pubs.acs.org/doi/abs/10.1021/jm4006884},

doi = {10.1021/jm4006884},

issn = {0022-2623},

year  = {2013},

date = {2013-08-01},

journal = {J. Med. Chem.},

volume = {56},

number = {15},

pages = {6234-6247},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Havlikova2013,

title = {Fluorone dyes have binding sites on both cytoplasmic and extracellular domains of Na,K-ATPase.},

author = {Marika Havlíková and Miroslav Huličiak and Václav Bazgier and Karel Berka and Martin Kubala},

url = {http://linkinghub.elsevier.com/retrieve/pii/S0005273612003781},

doi = {10.1016/j.bbamem.2012.10.029},

issn = {00052736},

year  = {2013},

date = {2013-02-01},

journal = {Biochim. Biophys. Acta, Biomembr.},

volume = {1828},

number = {2},

pages = {568-576},

keywords = {},

pubstate = {published},

tppubtype = {article}

}